We initiate coverage of Vicore Pharma with an OUTPERFORM recommendation and a TP of SEK43, nearly three times the current share price. Vicore is a clinical-stage Swedish biotech company focused on fibrotic orphan diseases. The key driver is lead asset C21, a highly selective small molecule agonist of the angiotensin II type 2 receptor (“AT2R”), in development for idiopathic pulmonary fibrosis (“IPF”), a rapidly progressing, fatal lung disease with few, sub-optimal treatment options that nevertheless generated c.$1.8bn in 2017E sales. C21 is due to start a Phase IIa proofof-concept trial in IPF in April / May and could enter a pivotal trial in 2020E, paving the way for regulatory approval in 2023E. We forecast peak sales of c.$1.4bn in 2030E and assume that Vicore enters a licensing deal in 2022E including $1bn in total upfront and milestone payments plus double-digit royalties on sales.

22 Mar 2018
Novel approach to tackle fibrotic orphan diseases

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Novel approach to tackle fibrotic orphan diseases
Vicore Pharma Holding AB (6Y4:FRA) | 0 0 0.0%
- Published:
22 Mar 2018 -
Author:
Brigitte de Lima, PHD CFA -
Pages:
28 -
We initiate coverage of Vicore Pharma with an OUTPERFORM recommendation and a TP of SEK43, nearly three times the current share price. Vicore is a clinical-stage Swedish biotech company focused on fibrotic orphan diseases. The key driver is lead asset C21, a highly selective small molecule agonist of the angiotensin II type 2 receptor (“AT2R”), in development for idiopathic pulmonary fibrosis (“IPF”), a rapidly progressing, fatal lung disease with few, sub-optimal treatment options that nevertheless generated c.$1.8bn in 2017E sales. C21 is due to start a Phase IIa proofof-concept trial in IPF in April / May and could enter a pivotal trial in 2020E, paving the way for regulatory approval in 2023E. We forecast peak sales of c.$1.4bn in 2030E and assume that Vicore enters a licensing deal in 2022E including $1bn in total upfront and milestone payments plus double-digit royalties on sales.