On November 10, 2025, Imunon, Inc. (IMNN) held an R&D Day and provided updates on the latest data for IMNN-001 along with the ongoing OVATION 3 trial. Multiple speakers at the event highlighted the ability of IMNN-001 to turn "cold" tumors "hot", its highly favorable benefit/risk profile, new translational data showing how IMNN-001 is taken up by macrophages in the peritoneal fluid that leads to a robust immune response, along with the statistical plan for the OVATION 3 trial. The company also recently presented at the SITC 40th Annual Meeting where new translational data from the OVATION 2 study demonstrated how IMNN-001 can remodel the tumor microenvironment through increased recruitment of CD8+ T cells. Recruitment for the OVATION 3 trial has been greater than anticipated at the four currently open centers and we anticipate another four centers being opened before the end of 2025.
