Reviva is a research and development pharmaceutical company with two portfolio compounds targeting nine indications. The candidates address multiple related mental disorders, rare diseases & other categories of un met need. Reviva's lead indication in schizophrenia with brilaroxazine (RP5063) completed its 1st Phase III trial & is set to begin its 2nd in 2025. Brilaroxazine is a novel multimodal modulator of serotonin, dopamine and nicotinic receptors, demonstrating improved efficacy and a better side effect profile compared to other antipsychotics. The drug class is established with over $10 billion in revenues. Unmet need persists in the category, related to efficacy, side effects & drug regimen compliance. Brilaroxazine's improved profile is ex pected to carve material share from the existing market and expand into untreated patients. Secondary can didate, RP1208, is in preclinical studies for depression and obesity. After agency review in the US and other jurisdictions, we anticipate NDA submission to the FDA in 2026 followed by regulatory submission in other territories. Our valuation as sumes commercializa tion in the US and rest of world following regulatory approval.
