Sareum Holdings PLC's (LON:SAR) Tim Mitchell tells Proactive London's Andrew Scott they're advancing initial discussions with potential licensees for its pre-clinical tyrosine kinase 2 (TYK2) / Janus kinase 1 (JAK1) inhibitor immunotherapies for autoimmune diseases and cancer. He says they're looking to complete investigational new drug-enabling work for at least one of its TYK2/JAK1 candidates by the end of the calendar year with a decision on an initial target to be made in the second half.