With first ABX464 data from Phase 2b in ulcerave colis ("UC”) expected in midMay and from Phase 2a in rheumatoid arthris end Q2, the next two months could be transformave for Abivax. As highlighted in the recent KOL webinar, while there are already mulple therapies, diagnosed largely in younger paents there is sll a substanal and growing unmet need in UC for a safe, effecve, convenient and well tolerated drug that can be used over many years. Orally delivered and proven safe in mulple trials, Phase 2a data already suggest ABX464 may outperform exisng UC therapies. With the IBD market already valued at $18bn and total an-inflammatory including RA at $90bn, posive readouts in UC and potenally RA should provide the basis for a major partnering deal. We reiterate our OUTPERFORM recommendaon and target €43 share target price.

23 Apr 2021
ABX464 potential therapy of choice in bowel disease

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ABX464 potential therapy of choice in bowel disease
Abivax SA (0RA9:LON) | 0 0 0.5% | Mkt Cap: 83.0m
- Published:
23 Apr 2021 -
Author:
Chris Redhead -
Pages:
5 -
With first ABX464 data from Phase 2b in ulcerave colis ("UC”) expected in midMay and from Phase 2a in rheumatoid arthris end Q2, the next two months could be transformave for Abivax. As highlighted in the recent KOL webinar, while there are already mulple therapies, diagnosed largely in younger paents there is sll a substanal and growing unmet need in UC for a safe, effecve, convenient and well tolerated drug that can be used over many years. Orally delivered and proven safe in mulple trials, Phase 2a data already suggest ABX464 may outperform exisng UC therapies. With the IBD market already valued at $18bn and total an-inflammatory including RA at $90bn, posive readouts in UC and potenally RA should provide the basis for a major partnering deal. We reiterate our OUTPERFORM recommendaon and target €43 share target price.