Final cohort results from Phio's PH-762 Phase 1b skin-cancer trial were favorable, with 100% tumor clearance in one patient, greater than 90% in a second, and greater than 50% in a third, coupled with a favorable safety review at the maximum dose.
The stock jumped on this news, before giving back more than all of the day's gain. We believe the announcement of a warrant exercise weighed on the stock price.
In addition, David H. Deming was named last week as Lead Independent Director, bringing biopharma investment-banking experience to the forefront.
Phio is expected to release earnings and provide a business update this month. The company does not typically announce the date ahead of time or hold an earnings call.
We maintain our estimates for 3Q:25 earnings, and raise our estimates going forward into 4Q;25 and 2026, as the financing we projected in 1Q:26 has been pulled forward.
We continue to assign a High-Risk rating, given the early stage of commercialization and history of net losses.
29 Nov 2025
Final Phio Phase 1b Study Cohort for Lead Asset PH-762 Delivers Favorable Tumor Clearance and Safety Result; Warrant Exercise Provides Liquidity Injection; Maintain 3Q:25 Estimates
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Final Phio Phase 1b Study Cohort for Lead Asset PH-762 Delivers Favorable Tumor Clearance and Safety Result; Warrant Exercise Provides Liquidity Injection; Maintain 3Q:25 Estimates
- Published:
29 Nov 2025 -
Author:
Alex Hantman -
Pages:
10 -
Final cohort results from Phio's PH-762 Phase 1b skin-cancer trial were favorable, with 100% tumor clearance in one patient, greater than 90% in a second, and greater than 50% in a third, coupled with a favorable safety review at the maximum dose.
The stock jumped on this news, before giving back more than all of the day's gain. We believe the announcement of a warrant exercise weighed on the stock price.
In addition, David H. Deming was named last week as Lead Independent Director, bringing biopharma investment-banking experience to the forefront.
Phio is expected to release earnings and provide a business update this month. The company does not typically announce the date ahead of time or hold an earnings call.
We maintain our estimates for 3Q:25 earnings, and raise our estimates going forward into 4Q;25 and 2026, as the financing we projected in 1Q:26 has been pulled forward.
We continue to assign a High-Risk rating, given the early stage of commercialization and history of net losses.